Vaccinium angustifolium is a low spreading deciduous shrub growing 5 to 60 cm (2 to 24 in) tall. Its rhizomes can lie dormant up to 100 years, and when given the adequate amount of sunlight, soil moisture, and oxygen content they will sprout. The leaves are glossy blue-green in summer, turning a variety of reds in the fall. The leaf shape is broad to elliptical. Buds are brownish red in stem axils. The flowers are white or pink, bell-shaped, 4 to 6 mm (0.16 to 0.24 in) long. The fruit is a small sweet dark blue to black berry, full of antioxidants and flavonoids. This plant grows best in wooded areas, old abandoned farmyards or open areas with well-drained acidic soils. In some areas it produces natural blueberry barrens, where it is practically the only species covering large areas.

Several buds may be on a healthy stem, and each bud can open up and have several blossoms. A blueberry field that has full plant coverage can have as many as 150 million blossoms per acre.

The Vaccinium angustifolium plant is fire-tolerant, and its numbers often increase in an area following a forest fire. Traditionally, blueberry growers burn their fields every few years to eliminate shrubs and fertilize the soil. In Acadian French, a blueberry field is known as a brûlis (from brûlé 'burnt') because of that technique, which is still in use.